Theme 1. Exposure: Transport and Transformations

Transport and Transformations controlled laboratory experiments elucidate fundamental principles determining nanoparticle (NP) surface chemistry, transport and transformation. Work in Theme 1 provides the foundation for understanding nanomaterial bioavailability, organismal responses, trophic transfer and impacts on ecosystem functions (Themes 2 and 3). Indeed, environmental and physiological transformations must be considered to perform reproducible, meaningful experiments assessing potential exposure and impacts of nanomaterials on organisms and ecosystems. The primary tasks in Theme 1 are to: 1) connect the chemistry and size-effects of NPs to their aggregation state and movement in the environment and, 2) characterize biological and chemical transformations of such materials as a basis for understanding environmental persistence, transport and bioavailability.

Goals: 

Work in Theme 1 provides the foundation for understanding nanomaterial bioavailability, organismal responses, trophic transfer and impacts on ecosystem functions (Themes 2 and 3). Indeed, environmental and physiological transformations must be considered to perform reproducible, meaningful experiments assessing potential exposure and impacts of nanomaterials on organisms and ecosystems.

Selected Publicaitons

J. H. Bisesi, Jr., Robinson, S. E. , Lavelle, C. M. , Ngo, T. , Castillo, B. , Crosby, H. , Liu, K. , Das, D. , Plazas-Tuttle, J. , Saleh, N. B. , Ferguson, P. L. , Denslow, N. D. , and Sabo-Attwood, T. , Influence of the Gastrointestinal Environment on the Bioavailability of Ethinyl Estradiol Sorbed to Single-Walled Carbon Nanotubes, Environ Sci TechnolEnviron Sci Technol, vol. 51, no. 2, pp. 948-957, 2017.
X. Gao, Spielman-Sun, E. , Rodrigues, S. M. , Casman, E. A. , and Lowry, G. V. , Time and Nanoparticle Concentration Affect the Extractability of Cu from CuO NP-Amended Soil, Environmental Science & TechnologyEnvironmental Science & Technology, 2017.
C. Jiang, Castellon, B. T. , Matson, C. W. , Aiken, G. R. , and Hsu-Kim, H. , Relative contributions of copper oxide nanoparticles and dissolved copper to Cu uptake kinetics of Gulf killifish (Fundulus grandis) embryos, Environmental Science & TechnologyEnvironmental Science & Technology, vol. 51, no. 3, pp. 1395-1404, 2017.
D. Wang, Wang, Z. , Lee, A. , Marr, L. C. , Heflin, J. R. , and Xu, Y. , Highly sensitive nano-aerosol detection based on the whispering-gallery-mode in cylindrical optical fiber resonators, Aerosol Science and TechnologyAerosol Science and Technology, vol. 50, pp. 1366-1374, 2016.
P. A. Holden, Gardea-Torresdey, J. L. , Klaessig, F. , Turco, R. F. , Mortimer, M. , Hund-Rinke, K. , Hubal, E. A. Cohen, Avery, D. , Barcelo, D. , Behra, R. , Cohen, Y. , Deydier-Stephan, L. , Ferguson, P. L. , Fernandes, T. F. , B. Harthorn, H. , Henderson, W. M. , Hoke, R. A. , Hristozov, D. , Johnston, J. M. , Kane, A. B. , Kapustka, L. , Keller, A. A. , Lenihan, H. S. , Lovell, W. , Murphy, C. J. , Nisbet, R. M. , Petersen, E. J. , Salinas, E. R. , Scheringer, M. , Sharma, M. , Speed, D. E. , Sultan, Y. , Westerhoff, P. , White, J. C. , Wiesner, M. R. , Wong, E. M. , Xing, B. , M. Horan, S. , Godwin, H. A. , and Nel, A. E. , Considerations of Environmentally Relevant Test Conditions for Improved Evaluation of Ecological Hazards of Engineered Nanomaterials, Environmental Science & TechnologyEnvironmental Science & TechnologyEnviron Sci Technol, vol. 50, pp. 6124-45, 2016.
N. K. Geitner, Marinakos, S. M. , Guo, C. , O’Brien, N. , and Wiesner, M. R. , Nanoparticle Surface Affinity as a Predictor of Trophic Transfer, Environmental Science & Technology, vol. 50, no. 13, pp. 6663 - 6669, 2016.
H. Wei, Willner, M. , Marr, L. , and Vikesland, P. , Highly stable SERS pH nanoprobes produced by co-solvent controlled AuNP aggregation, AnalystAnalyst, vol. 141, pp. 5159-5169, 2016.
L. F. Baker, King, R. S. , Unrine, J. M. , Castellon, B. T. , Lowry, G. V. , and Matson, C. W. , Press or pulse exposures determine the environmental fate of cerium nanoparticles in stream mesocosms, Environmental Toxicology and Chemistry, vol. 35, no. 5, pp. 1213–1223, 2016.
C. O. Hendren, Lowry, G. V. , Unrine, J. M. , and Wiesner, M. R. , A functional assay-based strategy for nanomaterial risk forecasting, Science of The Total Environment, 2015.
L. E. Barton, Auffan, M. , Durenkamp, M. , McGrath, S. , Bottero, J. - Y. , and Wiesner, M. R. , Monte Carlo simulations of the transformation and removal of Ag, TiO2, and ZnO nanoparticles in wastewater treatment and land application of biosolids, Science of The Total Environment, vol. 511, pp. 535 - 543, 2015.

Highlights