Impact of sulfidation on the bioavailability and toxicity of silver nanoparticles to Caenorhabditis elegans
|Title||Impact of sulfidation on the bioavailability and toxicity of silver nanoparticles to Caenorhabditis elegans|
|Publication Type||Journal Article|
|Year of Publication||2015|
|Authors||Starnes, DL, Unrine, JM, Starnes, CP, Collin, BE, Oostveen, EK, Ma, R, Lowry, GV, Bertsch, PM, Tsyusko, OV|
|Pagination||239 - 246|
Sulfidation is a major transformation product for manufactured silver nanoparticles (Ag-MNPs) in the wastewater treatment process. We studied the dissolution, uptake, and toxicity of Ag-MNP and sulfidized Ag-MNPs (sAg-MNPs) to a model soil organism, Caenorhabditis elegans. Our results show that reproduction was the most sensitive endpoint tested for both Ag-MNPs and sAg-MNPs. We also demonstrate that sulfidation not only decreases solubility of Ag-MNP, but also reduces the bioavailability of intact sAg-MNP. The relative contribution of released Ag+ compared to intact particles to toxicity was concentration dependent. At lower total Ag concentration, a greater proportion of the toxicity could be explained by dissolved Ag, whereas at higher total Ag concentration, the toxicity appeared to be dominated by particle specific effects.
|Short Title||Environmental Pollution|