I am interested in biological and physicochemical mechanisms driving organisms/nanomaterials interactions. I am also working on specific nanomaterial properties, aiming at designing safer nano-object for the health and the environment.
In view of studying these aspects, I am developing a multidisciplinary approach for the synthesis of nanomaterials, their physicochemical characterization, and the study of their interactions with cells and organisms. The tools I am using are multiscaled and mainly based on X-rays, (such as X-rays Absorption Spectroscopy, X-rays diffraction, X-Rays fluorescence microscopy or X-rays tomography) and microscopy (Atomic Force Microscopy and Enhanced-Dark Field Microscopy coupled to Hyperspectral Imaging).
A. Avellan, M. Auffan, A. Masion, C. Levard, M. Bertrand, J. Rose, C. Santaella, et W. Achouak, « Remote biodegradation of Ge-imogolite nanotubes controlled by the iron homeostasis of Pseudomonas brassicacearum », Environ. Sci. Technol., vol. 50, no 14, p. 7791‑7798, 2016b.
A. Avellan, C. Levard, J. Rose, M. Auffan, M. Bertrand, L. Olivi, C. Santaella, W. Achouak, et A. Masion, « Influence of structural defects of Ge-imogolite nanotubes on their toxicity towards Pseudomonas brassicacearum », Environ. Sci. Nano, vol. in press, 2016a.
S. van den Brule, E. Beckers, P. Chaurand, W. Liu, S. Ibouraadaten, M. Palmai-Pallag, F. Uwambayinema, Y. Yakoub, A. Avellan, C. Levard, V. Haufroid, E. Marbaix, A. Thill, D. Lison, et J. Rose, « Nanometer-long Ge-imogolite nanotubes cause sustained lung inflammation and fibrosis in rats », Part. Fibre Toxicol., vol. 11, no 1, p. 67, 2014b.
A. Avellan, C. Levard, N. Kumar, J. Rose, L. Olivi, A. Thill, P. Chaurand, D. Borschneck, et A. Masion, « Structural incorporation of iron into Ge–imogolite nanotubes: a promising step for innovative nanomaterials », RSC Adv., vol. 4, no 91, p. 49827‑49830, 2014a.