Uptake and retention of metallic nanoparticles in the Mediterranean mussel (Mytilus galloprovincialis)

TitleUptake and retention of metallic nanoparticles in the Mediterranean mussel (Mytilus galloprovincialis)
Publication TypeJournal Article
Year of Publication2013
AuthorsHull MS, Vikesland PJ, Schultz IR
JournalAquatic Toxicology
Volume140-141
Pagination89 - 97
Date Published9/2013
ISSN0166445X
Abstract

We measured the uptake, distribution and elimination of two types of metallic nanoparticles (MetNPs) by the aquatic mussel Mytilus galloprovincialis in static seawater column exposures. Test MetNPs included polyethylene glycol (PEG) functionalized Fe3O4 nanoparticles (PEG-FeOxNP) and PEG-functionalized cadmium-selenide quantum dots (PEG-Qdot). Exposure water was sampled at various times to assess MetNP clearance, and mussels were serially euthanized to assess uptake of MetNPs into the hemolymph, digestive gland, and remaining carcass. Results indicated that >90% of both types of MetNPs were taken up by mussels within 8 h of initial exposure. Nearly the entire retained dose of FeOxNPs and PEG-Qdots was deposited in the digestive gland. Our results provide important insights on the uptake and elimination kinetics of MetNPs in filter-feeding marine bivalves, and will be useful for subsequent development of toxicokinetic models to predict the kinetics of these processes.

DOI10.1016/j.aquatox.2013.05.005
Short TitleAquatic Toxicology